| SHORT COMMUNICATION |
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| Year : 1994 | Volume
: 26
| Issue : 3 | Page : 225-226 |
Alloxan-induced diabetes in rabbits and effect of a herbal formulation D-400
GP Dubey, SP Dixit, Singh Alok
Correspondence Address:
G P Dubey
 Source of Support: None, Conflict of Interest: None  | Check |
Adult male rabbits injected with alloxan (50 mg/kg, i.p.) were divided into two groups of nine each. One group received placebo and the other group an aqueous suspension of D-400, at the dose of 1gm/kg body weight orally daily for 36 weeks. Blood glucose, blood urea and serum creatinine were estimated initially and at every 6-weekly intervals. At the end of 36 weeks D-400 significantly prevented the rise in blood urea and serum creatinine levels as compared to the control. Although a rise in blood sugar was noticed in both the groups, the level of blood sugar after 36 weeks was significantly lower in the D-400 treated group. This shows the favourable response of D-400 against alloxan-induced renal damaae and hyperglycaeima.
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