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Year : 1993  |  Volume : 25  |  Issue : 3  |  Page : 165-166

Performance and psychotropic drugs: class room demonstration in clinical pharmacology

Correspondence Address:
N Saha

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Source of Support: None, Conflict of Interest: None

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In the present study, the effect of single dose administration of 4 mg lorazepam on psychomotor performance was demonstrated in 6 volunteers. Performance was measured using a battery of paper and pencil tests which included B-letter cancellation test, digit symbol substitution test, symbol copying test, serial addition and serial subtraction tests, All the tests were sensitive to detect the lorazepam induced impairment of psychomotor function. This can be used as a model experiment to demonstrate to the undergraduate medical students the effects of CNS depressant drugs in humans. The student can also become acquainted with the concepts of clinical pharmacology during the demonstration.


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