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 SHORT COMMUNICATION
Year : 1992  |  Volume : 24  |  Issue : 4  |  Page : 227-228

Evaluation of topical non-steroidal anti-inflammatory drugs using penetration enhancers



Correspondence Address:
R D Puri


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Several topical formulations of piroxicam (1% w/w) andibuprofen (5% w/w) were prepared Various penetration enhancers were incorporated in these tormulations and evaluated for antiinflammatory activity using carrageenin induced rat paw edema model. The maximum effect was seen when piroxicam and ibuprofen were combined with 3% azone and 5% N-methyl-2-pyrrolidone as enhancers, respectively.






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