| SHORT COMMUNICATION |
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| Year : 1992 | Volume
: 24
| Issue : 4 | Page : 227-228 |
Evaluation of topical non-steroidal anti-inflammatory drugs using penetration enhancers
RD Puri, NM Sanghavi
Correspondence Address:
R D Puri
 Source of Support: None, Conflict of Interest: None  | Check |
Several topical formulations of piroxicam (1% w/w) andibuprofen (5% w/w) were prepared Various penetration enhancers were incorporated in these tormulations and evaluated for antiinflammatory activity using carrageenin induced rat paw edema model. The maximum effect was seen when piroxicam and ibuprofen were combined with 3% azone and 5% N-methyl-2-pyrrolidone as enhancers, respectively.
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