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Year : 1992  |  Volume : 24  |  Issue : 3  |  Page : 178-180

Indirect excitatory actions of histamine on isolated chicken crop

Correspondence Address:
A K Kalra

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Source of Support: None, Conflict of Interest: None

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Histamine produced concentration-dependent contraction of isolated longitudinal smooth muscles of chicken crop. Histamine-induced contractions were antagonized non-competitively by atropine, hexamethonium, cocaine, methysergide, indomethacin and verapamil. Physostigmine slightly potentiated the excitatory action of histamine. Theophylline did not produce any appreciable effect on histamine response. These results indicate that histamine exerted its excitatory action by involving a number of mechanisms.


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