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Year : 1992  |  Volume : 24  |  Issue : 3  |  Page : 176-177

Acute effect of human placental extract on NADPH producing pathway in rat

Correspondence Address:
K K Banerjee

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Source of Support: None, Conflict of Interest: None

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The effect of 'Placentrex',a human placental extract, on glucose-6- phosphate dehydrogenase (GGPDH) activity in tissues like liver, kidney and brain of rats were studied. Single administration of 'Placentrex' produced a significant reduction in G6PDH activity at the dose of 0.4 ml/100 g body weight in all the tissues under observation. Its inhibitory effect has been found to be increasing with increased doses. It is concluded that long term use of 'Placentrex' may lead to deleterious effect.


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