IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 8574 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded120    
    Comments [Add]    

Recommend this journal


Year : 1992  |  Volume : 24  |  Issue : 3  |  Page : 154-157

Toxicological profile of fluvalinate - A synthetic pyrethroid

Correspondence Address:
S K Garg

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

The effect of fluvalinate (15 mg/kg, i.p) on pentobarbitone induced hypnosis and spontaneous locomotor activity in mice revealed pronounced CNS depressant effect of the compound. It produced negative inotropic and chronotropiceffects on the isolated frog heart. Spontaneous motility of isolated chicken ileum was reduced by fluvalinate in dose dependent manner. Fluvalinate (15 mg/kg, i.p) treatment for 15 days resulted in significant reduction in total leucocyte and absolute lymphocyte count. The test compound when administered for 15 days @ 15 mg/kg/day i.p., produced hepato-nephro toxicity and mild peripheral disintegration of the lymphoid nodules in spleen.


Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow