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Year : 1992  |  Volume : 24  |  Issue : 2  |  Page : 98-101

Efficacy of an ayurvedic formulation in rheumatoid arthritis: A double-blind, placebo-controlled, cross-over study

Correspondence Address:
R R Kulkarni

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Source of Support: None, Conflict of Interest: None

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The clinical efficacy of an Ayurvedic indigenous formulation containing Withania somnifera, Boswellia serrata, Curcuma longa and zinc, was evaluated in a randomized, double-blind, placebo controlled, cross-over study in 20 patients of rheumatoid arthritis. Treatment with the indigenous formulation for the period of 3 months produced significantly greater relief of pain, decreased morning stiffness, decrease in Ritche articular index and joint score. A significant drop in erythrocyte sedimentation rate was observed in the drug treated patients (P < 0.01). Nine out of 20 patients showed seroconversion at the end of three months treatment with indigenous drug. Radiological assessment, however, did not show any significant changes in both the groups. Side effects observed with this formulation did not necesitate withdrawal of treatment.


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