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Year : 1992  |  Volume : 24  |  Issue : 2  |  Page : 116-118

Selective toxicological studies of glycosidal fraction isolated from Maesa chisia D. Don Var. angustifolia hook F and Th

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Gomes Aparna

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Glycosidal fraction of the leaves of the plant Maesa chisia was examined in rats (100 mg/kg, p.o.) and mice (50 mg/kg, p.o.) after 21 days of administration for their safe use. It did not produce any significant changes in the body weight, food and water intake, haematological profile and histopathological studies of the major organs (liver, kidney, lung, heart, spleen, intestine) of both species. No significant changes in biochemical parameters (glucose, creatinine, SGOT, SGPT) were found as compared with control in rat. The above findings are likely to strengthen the safe use of the glycosidal fraction in rodents.


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