lexi
IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 2782 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1252    
    Printed81    
    Emailed0    
    PDF Downloaded83    
    Comments [Add]    

Recommend this journal

 

 RESEARCH PAPER
Year : 1991  |  Volume : 23  |  Issue : 4  |  Page : 247-252

Evidences for the presence of dopamine receptors in iris



Correspondence Address:
Y P Srivastava


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

1. Haloperidol is known to produce miosis by acting on receptors present in the iris. This study domonstrates the presence of dopamine receptors in the iris. 2. Dopamine given intracamerally produced dose-related mydriasis, and haloperidol was found to competitively antagonize this effect. 3. Apomorphine, another dopamine agonist, also produced dose-related mydriasis. 4. These observations suggest the presence of dopamine receptors in the iris. 5. Since the mydriasis was completely abolished after reserpinization and competetively antagonixed by phentolamine, it is proposed that these dopamine receptors are present presynaptically at the sympathetic nerve endings and are excitatory for norepinephrine release.






[PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow