| RESEARCH PAPER
|Year : 1991 | Volume
| Issue : 4 | Page : 208-213
Effect of norepinephrine on primary immune response to T-dependent antigen in poultry
S Rishi, BD Garg
1. The effect of in vivo administration of norepinephrine on different days varying from 1 to 8 of immunization on primary humoral immune response to T-dependent antigen in poultry has been studied.
2. Norepinephrine (NE) 1 mg/kg-1 i.v. exhibited an enhancing effect, maximum being on day 4 of immunization.The levels of IgM increased in all the groups up to day 8 whereas levels of IgG increased only when NE was given on days 6,7 or 8 of immunization.
3. The enhancing effect was found to be (-adrenoceptor mediated as it could be blocked by propranolol, a (-adrenoceptor antagonist.The (-adrenoceptor antagonist, phenolamine, failed to block this effect.
Source of Support: None, Conflict of Interest: None