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 RESEARCH PAPER
Year : 1991  |  Volume : 23  |  Issue : 4  |  Page : 208-213

Effect of norepinephrine on primary immune response to T-dependent antigen in poultry



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S Rishi


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1. The effect of in vivo administration of norepinephrine on different days varying from 1 to 8 of immunization on primary humoral immune response to T-dependent antigen in poultry has been studied. 2. Norepinephrine (NE) 1 mg/kg-1 i.v. exhibited an enhancing effect, maximum being on day 4 of immunization.The levels of IgM increased in all the groups up to day 8 whereas levels of IgG increased only when NE was given on days 6,7 or 8 of immunization. 3. The enhancing effect was found to be (-adrenoceptor mediated as it could be blocked by propranolol, a (-adrenoceptor antagonist.The (-adrenoceptor antagonist, phenolamine, failed to block this effect.






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