IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 15317 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded256    
    Comments [Add]    

Recommend this journal


Year : 1991  |  Volume : 23  |  Issue : 3  |  Page : 160-163

Pharmacological and biochemical effects of few indigenous drugs

Correspondence Address:
K S Santoshkumari

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

1. Effect of administration of Ayurveda drugs Nisakathakathi Kashayam (NK) and Rasnairandadi Kashayam (RK) and its mixture (2: 1 V/V) in a dose of 1 ml/kg body weight/day in normal, diabetic, diabetic hypertensive and diabetic hyper-cholesterolemic rabbits were studied. 2. No toxic reaction was observed in mice on administration of NK and RK. RK and the mixture of NK and RK caused decrease in the blood pressure of diabetic hypertensive rabbits, 3. RK increased acetylcholine induced spasm but NK did not. 4. NK showed +ve inotropic effect whereas RK first showed a cardiac arrest followed by a +ve inotropic effect. 5. NK contains 35 gm% total solid, 0.19 gm% total alkoloid and no zinc and copper. Whereas RK contains only 6.8 gm% total solid 0.32 gm% total alkaloid, 3.52 ppm copper and 1.87 ppm zinc. 6. Administration of NK and RK and its mixture to experimental rabbits decreased fasting blood glucose and serum cholesterol and the effect was more significant in the case of mixture.


Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow