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Year : 1991  |  Volume : 23  |  Issue : 2  |  Page : 99-103

A comparative evaluation of some anti-stress agents of plant origin

Correspondence Address:
N Singh

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Source of Support: None, Conflict of Interest: None

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1. Comparative evaluation of the anti-stress activity of Ocimum sanctum, Eleutherococcus senticosus and Panax ginseng was carried out in albino mice and rats in different experimental models of stress. 2. All the three drugs prevented various stress induced changes in these animals to a variable degree. 3. Anti-stress unit (ASU) of activity of the plants were determined by the ED, values of different tests. Taking ASU of Osimum sanctum as 1, the relative potency of Eleutherococcus senticosus and Panax ginseng was 0.83 and 0.53 respectively. Thus Osimum sanctum was found to be most potent anti-stress agent followed by Eleutherococcus senticosus and Panax ginseng. It had highest margin of safety also.


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