| SHORT COMMUNICATION
|Year : 1990 | Volume
| Issue : 2 | Page : 113-116
Pharmacological screening of some new 2 (substituted acetyl) Amino-5 Alkyl- 1, 3, 4 -Thiadiazoles
Mishra Pradeep, AK Shakva, RK Agrawal, GK Patnaik
1. Fifteen different 2 (substituted acetyl) amino-5-alkyl-I, 3, 4-thiadiazoles were synthesized.
2. These compounds were screened for spasmolytic and anti-inflammatory activities,
3. Compound AK-3, 2 (dimethyl amino acetyl) amino-5-propyl-1, 3, 4-thiadiazoles was found to possess potent spasmolytic activity.
4. Compound AK-5, 2 (diethyl amino acetyl) amino-5-ethyl 1, 3-4-thiadiazole was found to be an effective anti-inflammatory agent.
Source of Support: None, Conflict of Interest: None