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Year : 1989  |  Volume : 21  |  Issue : 4  |  Page : 159-162

Comparative efficacy of atenolol alone and in combination with hydrochlorthiazide in essential hypertension



Correspondence Address:
M U Rabbani


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1. This study included 54 patients of essential hypertension. 2. 17 patients received atenolol combined with hydrochlorthiazide and 37 patients received atenolol alone. 3. Significant reduction in blood pressure was observed with both forms of treatment. 4. Fall in blood pressure was greater with combination therapy. 5. Weakness and giddiness were the most common adverse effects and addition of thiazide diuretic did not increase the incidence of adverse events. 6. It is concluded that hydrochlorthiazide increases the anti-hypertensive efficacy of atenolol without increasing adverse reactions.






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