| RESEARCH PAPER |
|
| Year : 1989 | Volume
: 21
| Issue : 4 | Page : 144-152 |
A study on the selectivity of action of (+) INPEA and vasicine in different isolated tissue preparations
C Madappa, A Sankaranarayanan, PL Sharma
Correspondence Address:
C Madappa
 Source of Support: None, Conflict of Interest: None  | Check |
1. The action of (+) INPEA and vasicine on the isolated rat uterus, guinea pig uterus, rat mammary gland, guinea pig ileum and guinea pig tracheal chain were studied.
2. (+) INPEA (1' g/ml and 10 'g/ml) and vasicine (1 'g/ml and 10 'g/ml) elicited a stimulant action, with an increase in amplitude and frequency of contractions in the isolated rat and guinea pig uterus.
3. Vasicine (1 'g/ml) potentiated the action of oxytocin in isolated rat mammary strip preparation.
4. Vasicine (1 'g/ml) potentiated the action of barium chloride evoked contractions in guinea pig ileum.
5. The study indicates that ( + ) INPEA shows selectivity for uterine tissue.
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