RESEARCH PAPER |
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Year : 1988 | Volume
: 20
| Issue : 2 | Page : 90-94 |
Paracetamol disposition in rat after oral intake of methaqualone
KP Gupta, KP Bhargava
Correspondence Address:
K P Gupta
 Source of Support: None, Conflict of Interest: None  | Check |

1. The effect of oral feeding of methaqualone on the pharmacokinetica of paracetamol diapoeition waa studied.
2. Rats given methaqualone (60 mg/kg) orally for a prolonged period were given in addition a single dose of paracetamol (100 mg/kg ip) and pharmacokinetic profile of paracetamol in the plasma and drug levels in liver were estimated.
3.Repeated oral methaqualone intake increased parecetamol disposition.
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