| RESEARCH PAPER |
|
| Year : 1988 | Volume
: 20
| Issue : 2 | Page : 90-94 |
Paracetamol disposition in rat after oral intake of methaqualone
KP Gupta, KP Bhargava
Correspondence Address:
K P Gupta
 Source of Support: None, Conflict of Interest: None  | Check |
1. The effect of oral feeding of methaqualone on the pharmacokinetica of paracetamol diapoeition waa studied.
2. Rats given methaqualone (60 mg/kg) orally for a prolonged period were given in addition a single dose of paracetamol (100 mg/kg ip) and pharmacokinetic profile of paracetamol in the plasma and drug levels in liver were estimated.
3.Repeated oral methaqualone intake increased parecetamol disposition.
[PDF]*
|
