| RESEARCH PAPER
|Year : 1988 | Volume
| Issue : 2 | Page : 90-94
Paracetamol disposition in rat after oral intake of methaqualone
KP Gupta, KP Bhargava
1. The effect of oral feeding of methaqualone on the pharmacokinetica of paracetamol diapoeition waa studied.
2. Rats given methaqualone (60 mg/kg) orally for a prolonged period were given in addition a single dose of paracetamol (100 mg/kg ip) and pharmacokinetic profile of paracetamol in the plasma and drug levels in liver were estimated.
3.Repeated oral methaqualone intake increased parecetamol disposition.
K P Gupta
Source of Support: None, Conflict of Interest: None