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Year : 1988  |  Volume : 20  |  Issue : 2  |  Page : 152-158

Effect of zinc administration in acne vulgaris

Correspondence Address:
J Pohit

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Source of Support: None, Conflict of Interest: None

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1. Four experiments wereconduted in whichelementalzincwasorallyadministeredasZnSo4.7H2O dissolvedin water to acne vulgaris patients at the following doses for the given durations:froup A-25mg for 12 weeks,group B-50 mg for 5 weeks, group C-50 mg for 12 weeks and group D-100 mg for 12 weeks. 2. The zinc status of the patients was examined before and after treatment by measuring zinc in serum erythrocyte hair and nail;serum alkaline phosphatase and ribonuclease activities; blooduresandrissofserum zincfrom the fasting level 1 hour after oral administration of 5 mg elemental zinc. 3. There was approximately 50% fell of acne severity et the completion of all zinc treatment schedules. 4. considering the clinical improvement repair of the existing zinc deficit and side reactions the regimen of 50 mg zinc per day for 12 weeks seemed to be safe end effective.


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