| RESEARCH PAPER |
|
| Year : 1988 | Volume
: 20
| Issue : 2 | Page : 143-151 |
Pharmacological actions of vulpunic acid, a lichen metabolite
Rao AVN Appa, MC Prabhakar
Correspondence Address:
Rao AVN Appa
 Source of Support: None, Conflict of Interest: None  | Check |
1. Vulpinic acid (VA) isolated from the rare Himalayan Lichen Alectoris Virens exhibited hypotensive. anti-inflammatory. analgesic. anti-spasmodic (non-specific) and neuromuscular junction blocking properties.
2. Hypotensive effect of VA is attributed to its direct cardiac depressant action coupled with its property of: peripheral vasodilatation.
3. Anti-inflammatory effect of VA is attributed to its anti-histaminic and anti-serotonin properties.
4.The mechanism of action of VA at the neuromuscular junction appears to be complex.
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