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Year : 1988  |  Volume : 20  |  Issue : 2  |  Page : 114-121

Effects of cocaine and morphine on vision in rabbits

Correspondence Address:
Y K Purandare

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Source of Support: None, Conflict of Interest: None

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1. This study investigated effects of two drugs of abuse. viz. cocaine and morphine on two selected parameters of visual function in rabbits. The e-end-b- wave amplitudes of electroretinogram (ERG), and the wavelength of maximum absorbance (( max.) of the major photosensitive pigment, rhodopsin were studied. 2. There was reduction of a - and b - wave amplitudes under the influence of cocaine. end increase of a - end b-wave amplitudes under the influence of morphine. 3. ER 3 pattern wee distorted by both drugs. 4. High correlation was found between changes of a - end b-wave amplitudes end drug dose levels. 5. ( max. of rhodopsin remained unchanged under the influence of either durg.


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