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Year : 1987  |  Volume : 19  |  Issue : 3  |  Page : 225-229

In vitro studies on protein binding of rifampicin

Correspondence Address:
Polasa Kalpagam

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Source of Support: None, Conflict of Interest: None

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1. Protein binding of rifampicin to varying albumin concentrations was carried out in vitro. Effect on other antitubercular drugs on protein binding of rifampicin was also studied. 2. The results indicated that rifampicin binding was influenced by albumin concentration, suggesting that it was chiefly bound to albumin. 3. Presence of other antitubercular drugs along with rifampicin decreased the percentage of bound rifampicin.


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