IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 1560 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded75    
    Comments [Add]    

Recommend this journal


Year : 1987  |  Volume : 19  |  Issue : 2  |  Page : 130-133

Effect of scoparone on tissue catecholamine content

Correspondence Address:
M L Sharma

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

1. The effect of scoparone on catecholamine content of adrenal glands, spleen, brain and intestinal tissues of rats was investigated. 2. A single oral dose of scoparone (100 mg/kg-1) produced reduction of catecholamine content of adrenal glands and spleen without affecting that of brain, heart and small intestines. 3. On repeated oral administration also, it lowered the catecholamine content of the adrenal glands but not that of brain. 4. The catecholamine lowering effect appeared within 6h, and was maximum at 24 h. The hypotensive and tranquillosedative effects of scoparone appeared within 15-20 min after oral administration and lasted for 4-6 h.The pharmacological effects of scoparone, therefore, appear to be independent of its catecholamine depleting action.


Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow