| RESEARCH PAPER |
|
| Year : 1987 | Volume
: 19
| Issue : 2 | Page : 117-123 |
Altered digoxin levels in diabetic patients with congestive cardiac failure
RK Goyal, SM Jain, JJ Sheth, KC Dave, HC Mehta
Correspondence Address:
R K Goyal
 Source of Support: None, Conflict of Interest: None  | Check |
1. The present investigation was undertaken to study the influence of diabetes mellitus on digozin levels in patients with congestive cardiac failure.
2. Serum digoxin levels were found to be significantly higher in diabetics (1.35 ( 0.2 ng/ml) as compared to nondiabetics (0.4 ( 0.04 ng/ml), with higher values in female patients as compared to males.
3. There was a correlation (r=0.5) between increase in digoxin levels andincrease in glycosylated haemoglobin value.
4. It is suggested that dosage regimes of the glycoside should be redesigned in diabetic patients to reduce the digoxin morbidity and mortality.
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