| RESEARCH PAPER
|Year : 1986 | Volume
| Issue : 4 | Page : 239-241
Gentamicin penetration in human aqueous humor after intramuscular, topical and subconjunctival administration
S Kumar, GL Dhar, G Bano, RK Raina
1. The penetration of gentamicin in aqueous humor after different routes was investigated in 60 patients of uncomplicated senile cataract.
2. Systemic and topical administration of aminoglycoside did not produce detectable levels of the drug in aqueous humor.
3. The antibiotic appeared in aqueous humor after 15 minutes of administration by subconjunctival route and maximum concentration (Cmax) was attained at 1 hour. The effective concentration of the drug was detected for as long as 18 hours after subconjunctival injection. .
Source of Support: None, Conflict of Interest: None