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Year : 1986  |  Volume : 18  |  Issue : 3  |  Page : 175-177

The bronchorelaxant effect of oxytocin in guinea pigs

Correspondence Address:
Chandra Dinesh

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Source of Support: None, Conflict of Interest: None

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1. Bronchorelaxant effect of graded doses oxytocin in guinea pigs was studied employing in vitro and in vivo experiments 2. In vitro studies the 50% relaxant dose (EC 50) of oxytocin against histamine, carbachol and barium chloride were in close approximation. Lndomethacin pretreatment and compound SC 19220 increased the EC 50 of oxytocin. 3. In vivo experiments ip oxytocin prolonged the preconvulsive time.


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