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Year : 1986  |  Volume : 18  |  Issue : 2  |  Page : 73-77

Studies on cataractogenesis in rats with alloxan-induced diabetes

Correspondence Address:
U M Rawal

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Source of Support: None, Conflict of Interest: None

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1. The levels of deoxyribonuclic acid (DNA), ribonucleic acid (RNA) and total proteins in blood, aqueous humor, lens and electrolytes and water content in lens of normal as well as alloxan-treated rats have been determined. 2. A decrease in the levels of DNA, RNA and total proteins were observed in blood, aqueous humor and lenses obtained from rats pretreated with alloxan. Although, the average concentrations of DNA, RNA and total proteins in aqueous humor is higher than in the blood. 3. In contrast to normal lenses, alloxan-induced, cataractous lenses showed an increase in sodium, calcium, water content and a fall in potassium content. 4. Role of DNA, RNA, total proteins, electrolytes and water in normal lens and its reduction or change in cataractous condition has been discussed.


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