| RESEARCH PAPER
|Year : 1986 | Volume
| Issue : 2 | Page : 68-72
Investigating a possible relationship between pain sensitivity and hypertension
JS Hutchinson, K Rambadran, ML Kong, JYH Chan
1. Blood pressures by a tail plethysmographic method without anaesthesia and pain sensitivity over a range of temperatures using both the tail flick and hot plate methods in male spontaneously hypertensive rats (SHR), normotensive Wistar-Kyoto (WK) two kidney, one clip renovascular Sprague-Dawley rats (SDLRAS) and sham-operated Sprague-Dawley rats (SDSHAM) were recorded.
2. Latency to paw lick or jump was greater in SHR than any other group at 54oC This longer latency correlated significantly and positively with tail blood pressure.
3. It therefore seems that genetic factors, blood pressure and pain sensitivity may be related.
J S Hutchinson
Source of Support: None, Conflict of Interest: None