IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 11268 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded168    
    Comments [Add]    

Recommend this journal


Year : 1985  |  Volume : 17  |  Issue : 4  |  Page : 224-228

Effect of nonsteroidal anti-inflammatory drugs on (NSAIDS) on diuretic property of hydorchlorthiarzide

Correspondence Address:
G F Shah

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

1. Effects of nonsteroidal anti-inflammatory drugs (NSAIDS) on hydrochlorothiazide (HT) induced urine volume, urinary sodium, potassium and creatinine excretion were examined in conscious rats. 2. The diuretic activity, and the increased urinary sodium and potassium excretion elicited by HT (2.5 and 5 mg/kg) were inhibited after oral administration of NSAlDS like indomethacin (ID), oxyphenbutazone (OPB), ibuprofen (IBF) and naproxen (NAP), in doses which inhibited the rat carrageenin induced hind paw oedema. 3. Ibuprofen was most Potent and Naproxen was least Poent in antagonising both diuretic and Natriuretic activity.


Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow