| RESEARCH PAPER |
|
| Year : 1985 | Volume
: 17
| Issue : 3 | Page : 155-157 |
Local anaesthetic activity of some parasubstituted acetophenone mannich bases
SC Chaturvedi, GK Patnaik, BN Dhawan, VK Dixit
Correspondence Address:
S C Chaturvedi
 Source of Support: None, Conflict of Interest: None  | Check |
1. Twenty five Mannich bases of para substituted acetophenones were synthesized and tested for local anaesthetic activity in rabbits and guineapigs.
2 All the compounds of dibenzyl series showed significant surface and infiltration anaesthetic activity.
3. In the piperidine series only compound (-piperidinoethyl p-chlorophenyl ketone HCI showed local anaesthetic activity. This compound did not possess any local irritant effect.
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