| RESEARCH PAPER
|Year : 1985 | Volume
| Issue : 3 | Page : 155-157
Local anaesthetic activity of some parasubstituted acetophenone mannich bases
SC Chaturvedi, GK Patnaik, BN Dhawan, VK Dixit
1. Twenty five Mannich bases of para substituted acetophenones were synthesized and tested for local anaesthetic activity in rabbits and guineapigs.
2 All the compounds of dibenzyl series showed significant surface and infiltration anaesthetic activity.
3. In the piperidine series only compound (-piperidinoethyl p-chlorophenyl ketone HCI showed local anaesthetic activity. This compound did not possess any local irritant effect.
S C Chaturvedi
Source of Support: None, Conflict of Interest: None