| RESEARCH PAPER |
|
| Year : 1985 | Volume
: 17
| Issue : 3 | Page : 148-151 |
Pharmacodynamic interaction between penbutolol and alcohol
H Allain, Pereira LM Pinto, RD Kulkarni
Correspondence Address:
H Allain
 Source of Support: None, Conflict of Interest: None  | Check |
1. Penbutolol, a new, centrally-active (-blocking agent has been studied for its interaction with alcohol.
2. Alcohol (75(proof whisky) as 0.8 mg/kg was administered with 20 mg. penbutolol or placebo in double-blind crossover to 6 volunteers.
3. Psychomotor tests of performance did not reveal any significant penbutolol-alcohol interaction.
4. Peak changes in psychomotor performance coincided under both treatment conditions with peak serum alcohol levels.
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