| RESEARCH PAPER
|Year : 1985 | Volume
| Issue : 3 | Page : 148-151
Pharmacodynamic interaction between penbutolol and alcohol
H Allain, Pereira LM Pinto, RD Kulkarni
1. Penbutolol, a new, centrally-active (-blocking agent has been studied for its interaction with alcohol.
2. Alcohol (75(proof whisky) as 0.8 mg/kg was administered with 20 mg. penbutolol or placebo in double-blind crossover to 6 volunteers.
3. Psychomotor tests of performance did not reveal any significant penbutolol-alcohol interaction.
4. Peak changes in psychomotor performance coincided under both treatment conditions with peak serum alcohol levels.
Source of Support: None, Conflict of Interest: None