| RESEARCH PAPER
|Year : 1985 | Volume
| Issue : 3 | Page : 127-131
Effect of propranolol on platelet aggregation
A Ray, VS Gupta, M Alkondon, P Sen
1. Propranolol ( 5O, 100 and 200, (M) produced a dose related inhibition of platelet aggregation induced by ADP (3(M) and adrenaline (16(M).
2. Timolol upto a concentration of 200 (M had no significant effect on either model of aggregation.
3. Propranolol also significantly inhibited the rat paw oedema induced by carrageenan.
4. It is inferred that propranolol has an anti-platelet aggregatory effect which is unrelated to beta adrenoceptor blockade and could be due an anti-prostaglandin effect of the drug.
Source of Support: None, Conflict of Interest: None