| SHORT COMMUNICATION |
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| Year : 1985 | Volume
: 17
| Issue : 2 | Page : 113-115 |
Anti-inflammatory activity of substituted guanidine hydrochlorides
Saxena Archna, Aron Rina, SC Mehra, SK Tandan
Correspondence Address:
Saxena Archna
 Source of Support: None, Conflict of Interest: None  | Check |
1. Twelve different substituted guanidines were prepared by the condensation of different heterocyclic moieties with different aryl cyanamides.
2. Compounds were screened for anti-inflammatory activity and compared with standard drug phenylbutazone.
3. Ten compounds showed significant anti-inflammatory activity and compound IV, N-P-anisyl-N'-5-phenyl-1,3,4-oxadiazol-2-yl guanidine hydrochloride, was the most potent In carrageenin-induced oedema.
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