IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 4348 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded71    
    Comments [Add]    

Recommend this journal


Year : 1985  |  Volume : 17  |  Issue : 2  |  Page : 108-112

Behavioural evidence for direct stimulation of rat brain 5-Hydroxytryptamine receptors by ergometrine

Correspondence Address:
T R Bapat

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

1. Ergometrine produced a behavioural syndrome in the rat which was characterized by head and body shakes, lateral head weaving, forepaw treading, hindlimb abduction and Straub tail. 2. Pretreatment with 5-HT receptor antagonists, cyproheptadine and methysergide, significantly decreased the intensity of the behavioural syndrome produced by ergometrine. 3. Pretreatment with p-chlorophenylalanine and clomipramine significantly decreased the intensity of the behavioural syndromes induced by fenfluramine and p-chloramphetamine but had no significant effect on the intensity of the behavioural syndrome produced by ergometrine. 4. The results indicate that ergometrine produces the 5-HT mediated behavioural syndrome by directly stimulating the central 5-HT receptors.


Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow