IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 8058 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1724    
    Printed119    
    Emailed0    
    PDF Downloaded84    
    Comments [Add]    

Recommend this journal

 

 RESEARCH PAPER
Year : 1985  |  Volume : 17  |  Issue : 1  |  Page : 42-50

Effect of hypovolemia and hypertonicity on the ultrastructure and function of neurohypophysis in the mastomys natalensis



Correspondence Address:
K Chakravarty


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

1. The relative effects of blood volume contraction and hypertonicity on the vasopressin content and ultrastructure of the neural lobe have been examined after daily consecutive administration of polyethelene glycol (PEG) and hypertonic NaCl solution to mastromys natalensis. 2. Treatment with PEG and hypertonic saline caused a significant decrease in the total vasopressin content of the neural lobe (187(41 and 255(45 mU. neural lobe respectively) as compared to that of the control value (542(56 mU/neural lobe). 3. The decrease is correlated with the depletion of neurosecretory granules as observed under the electron microscope. 4. An interesting finding relates to the fact that hypovolemia not only stimulates the release of vasopressin but also effects the lipid content of the pituicytes. 5. The present studies are in agreement with the findings of the other workers in mammalian species. However, in this species of animals the activation of volume receptors is more predominent than that of Osmoreceptors.






[PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow