| RESEARCH PAPER |
|
| Year : 1984 | Volume
: 16
| Issue : 3 | Page : 129-131 |
Effect of propranolol on aggressive behaviour in rats
A Ray, M Alkondon, P Sen
Correspondence Address:
A Ray
 Source of Support: None, Conflict of Interest: None  | Check |
1. (Propranolol in doses of 1 and 3 mg/kg facilitated whereas 10 and 30 mg/kg inhibited footshock aggression (FSA) in rats.
2. Atropine but not atropine methylnitrate antagonised the antiaggressive effect of (() propranolol (IO mg/kg) wlthout affecting the facilitatory affect on FSA.
3. Racemic propranolol (1 and 10 mg/kg) also antagonised reserpine apomorphine aggression.
4. It is suggested that central cholinergic as well as dopaminergic mechanisms could be involved in the anti-aggressive effect of propranolol.
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