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Year : 1984  |  Volume : 16  |  Issue : 2  |  Page : 107-108

Effect of folic acid pretreatment on convulsions in mice

Correspondence Address:
R S Ranade

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Source of Support: None, Conflict of Interest: None

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1. The effect of folic acid pretreatment on the experimentally induced convulsions in mice; and on the protection afforded by ethosuximide and phenytoin against these convulsions was investigated. 2. Folic acid per se did not exhibit any convulsant effect 3. Folic acid for three days predisposed, the animals to experimental convulsions and reduced the anticonvulsant activity of ethosuximide and phenytoin.


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