| RESEARCH PAPER |
|
| Year : 1982 | Volume
: 14
| Issue : 4 | Page : 305-308 |
In vitro hemolytic property of substituted phenothiazines
AK Khasnobis, J Saha, BP Mukherjee
Correspondence Address:
A K Khasnobis
 Source of Support: None, Conflict of Interest: None  | Check |
In vitro hemolytic property of four commonly used substituted phenothiazine derivatives were studied on rabbit's washed erythrocytes, in isotonic saline. substitution of SCH2 group in place of H in position 2 of the phenothiazine ring, markedly increased the hemolytic activity, when compared with CF3 or Cl- substitution in the same position. Hemolytic property of these compounds also increased with the increase of incubation time and temperature.
[PDF]*
|
