| RESEARCH PAPER |
|
| Year : 1982 | Volume
: 14
| Issue : 4 | Page : 289-292 |
Distribution of chloramphenicol in blood and milk after oral administration in goat
BK Roy, NC Banerjee, SN Pandey
Correspondence Address:
B K Roy
 Source of Support: None, Conflict of Interest: None  | Check |
In goats, single dose oral administration of chloramphenicol did not produce therapeutic blood levels of the drug at 25mg and 50 mg/kg bw but at 100 mg and 200 mg/kg it produced therapeutic antimicrobial levels for 24 h and for more than 24 h, respectively. Single oral dose at 100 mg and 200 mg/kg gave therapeutic milk levels for 3 to 24 h and 1 h to 48 h, respectively. Both blood and milk were free from the drug at 72 h post administration after 100 and 200 mg/kg single oral doses. Species difference with regard to drug adsorptions from G. I. tract has been Suggested.
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