| RESEARCH PAPER |
|
| Year : 1982 | Volume
: 14
| Issue : 3 | Page : 229-232 |
Effect of pyrantel pamoate on the development of hook-worm
KC Singhal, RR Gupta, PN Saxena, Kumar Anil
Correspondence Address:
K C Singhal
 Source of Support: None, Conflict of Interest: None  | Check |
Pyrantel pamoate. a broad spectrum anthelmintic, was investigated for its effect on the developmental stages of sheep hook worm, Haemonchus controlus.
Addition of pyrantel pamoate to the faeces charcoal mixture caused concentration-related inhibition of transformation of Haemonchus contorlus seggs to infective larvae, the LC50 and LC90 being 54.95 ñ 6.90 and 400.00 ñ 49.10 mcg, respectively. On infective larvae, pyrantel pamoate produced contracture and decrease in motility leading to irreversible. paralysis.
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