| RESEARCH PAPER
|Year : 1982 | Volume
| Issue : 3 | Page : 229-232
Effect of pyrantel pamoate on the development of hook-worm
KC Singhal, RR Gupta, PN Saxena, Kumar Anil
Pyrantel pamoate. a broad spectrum anthelmintic, was investigated for its effect on the developmental stages of sheep hook worm, Haemonchus controlus.
Addition of pyrantel pamoate to the faeces charcoal mixture caused concentration-related inhibition of transformation of Haemonchus contorlus seggs to infective larvae, the LC50 and LC90 being 54.95 ˝ 6.90 and 400.00 ˝ 49.10 mcg, respectively. On infective larvae, pyrantel pamoate produced contracture and decrease in motility leading to irreversible. paralysis.
K C Singhal
Source of Support: None, Conflict of Interest: None