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Year : 1982  |  Volume : 14  |  Issue : 3  |  Page : 223-228

Evaluation of diazepam in the management of tetanus

Correspondence Address:
N Gangadharan

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Source of Support: None, Conflict of Interest: None

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A prospective study was carried out in 44 cases of adult tetanus, to evaluate the therapeutic efficacy of diazepam as compared to the standard drugs, keeping all other therapeutic measures similar and allocating the patients in a random fashion. There were no significant differences in the incidence of mortality and the time needed to control spasms, between patients receiving diazepam alone and standard drugs. A shorter incubation period, period of onset, presence of pyrexia and spasms carried a higher mortality rate irrespective of the line of management. The results of our study suggest that use of diazepam as a single effective agent may not be superior to standard drugs in the management of tetanus.


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