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Year : 1982  |  Volume : 14  |  Issue : 2  |  Page : 177-182

Synthesis and CNS activity of 4-Aryl-1-p [(substituted benzamido)-benzoyl]-piperazine

Correspondence Address:
Agarwal Rajesh

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Source of Support: None, Conflict of Interest: None

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Twelve title compounds (III) were synthesised by the aroylation of the 4-aryl-1-(p-amino benzoyl)-piperaxines (I I), which have, inturn, been prepared by the reduction of respective 4-aryl I-(p-nitro benzoyl)-piperazines (I). The structures of the new compounds were confirmed by elemental analysis and the IR and PMR spectroscopy. Eight of the title compounds were found to be CNS stimulants and the rest four, CNS depressants.


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