IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 1683 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded128    
    Comments [Add]    

Recommend this journal


Year : 1981  |  Volume : 13  |  Issue : 4  |  Page : 325-331

Chemical and pharmacological studies on Solanum giganteum jacq

Correspondence Address:
Y V Rao

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

A steroidal alkaloid with an additional-hydroxy and aminogroup was isolated from roots of Solanum giganteum Jacq (N. 0. Solanaceae). The compound decreased spontaneous motor activity and enhanced pentobarbitone hypnosis in albino mice. It produced spasmogenic responses on isolated smooth muscles like rat fundus and oestronised rat uterus and positive inotorpic effect on perfused frog's heart. Hypnotic potentiating effect in mice and spasmogenic responses on isolated smooth muscles were blocked by methysergide and BW501 C67 respectively suggesting that the compound possesses serotonin-like activity.


Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow