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Year : 1981  |  Volume : 13  |  Issue : 2  |  Page : 153-158

Preliminary pharmacological screening of Erythrina variegata Var. Orientails (syn. E. indica) seed

Correspondence Address:
G K Chatterjee

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Source of Support: None, Conflict of Interest: None

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The aqueous extract of the seeds of Erythrina variegata Var. Orientalis (Sym.E. indica) produced a sharp fall in b. p. Higher dose of the extract completely stopped the heart. It also produced a contraction of isolated guineapig ileum. The fall in b.p. and contraction of ileum were completely blocked by an antihistaminic agent-diphenhydramine. The extract did not show any CNS activity, since it neither affected the barbiturate induced sleeping time nor protected the penteylene tetrazol induced convulsions although it depressed the respiration at higher doses but stimulate the same in smaller doses in guineapigs.


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