IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 440 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded104    
    Comments [Add]    

Recommend this journal


Year : 1980  |  Volume : 12  |  Issue : 3  |  Page : 201-204

Comparative effects of gossypin and phenylbutazone on the temporal characteristics of carrageenin induced paw oedema and increased vascular permeability in rat

Correspondence Address:
N S Parmar

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

. The effect of gossypin in comparison with phenylbutazone has been studied on the quantitative temporal characteristics of carrageenin induced rat paw oedema and protein extravasation. Both parameters showed a biphasic response with identical time courses, indicating that the protein extravasation took place throughout the reaction and that it was proportional to the severity of paw swelling. Gossypin significantly reduced initial as well as late phases of paw oedema and protein extravasation, while phenylbutazone failed to reduce the initial increase of vascular permeability in response to carrageenin. Possible difference in the mechanism of action of gossypin and phenylbutazone and the role of mediators involved in the inflammatory process have been discussed


Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow