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Year : 1979  |  Volume : 11  |  Issue : 2  |  Page : 135-138

The anti-histaminic activity of (+)-cyanidanol-3 on isolated guinea pig ileum

Correspondence Address:
S Ramaswamy

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Source of Support: None, Conflict of Interest: None

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(+)-Cyanidanol-3 was tested for its in vitro antihistaminic activity on isolated guineapig ileum. It inhibited histamine induced contractions without affecting those of acetylcholine, 5-hydro-xytryptamine and potassium chloride. It is concluded that (+)-Cyanidanol-3 produces a relatively specific antihistaminic activity which may be mediated through H1-and H2-receptors.


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