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Year : 1978  |  Volume : 10  |  Issue : 4  |  Page : 257-264

Effect of betel nut constituents on sulfhydryl metabolism

Correspondence Address:
N M Shivapurkar

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Source of Support: None, Conflict of Interest: None

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. In order to study the effect of different constituents of betel nut on sulfhydryl metabolism. betel nut aqueous extract, polyphenol fraction and arecoline, an important alkaloid of betel nut were injected i.p. to Swiss mice. Glutathione, protein-SH and protein-SH+S-S contents were measured in liver, lung, kidney and muscle tissues. Tannic acid was injected as a standard polyphenol for comparison. Betel nut aqueous extract, polyphenol fraction and tannic acid increased glutathione content while arecoline decreased the same in almost all the tissues. All the test substances decreased the protein-SH content in majority of the tissues studied.


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