| SHORT COMMUNICATION |
|
| Year : 1977 | Volume
: 9
| Issue : 4 | Page : 305-309 |
Synthesis and pharmacology of 5-(NN-(Dialkylamino)-acetamido)-3,4-dimethyl isoxazoles
JP Trivedi, TP Gandhi, VC Patel
Correspondence Address:
J P Trivedi
 Source of Support: None, Conflict of Interest: None  | Check |
Eight isoxazoles (1 to 8) were synthesised in our laboratory. Five compounds (1 to 5) were selected for pharmacological screening. All the compounds showed local anaesthetic, spasmolytic and anti-epileptic activity. Dibenzylamino derivative was found to be most potent. less irritant and less toxic compound comparable to lignocaine.
[PDF]*
|
