| SHORT COMMUNICATION
|Year : 1977 | Volume
| Issue : 4 | Page : 305-309
Synthesis and pharmacology of 5-(NN-(Dialkylamino)-acetamido)-3,4-dimethyl isoxazoles
JP Trivedi, TP Gandhi, VC Patel
Eight isoxazoles (1 to 8) were synthesised in our laboratory. Five compounds (1 to 5) were selected for pharmacological screening. All the compounds showed local anaesthetic, spasmolytic and anti-epileptic activity. Dibenzylamino derivative was found to be most potent. less irritant and less toxic compound comparable to lignocaine.
J P Trivedi
Source of Support: None, Conflict of Interest: None