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Year : 1977  |  Volume : 9  |  Issue : 3  |  Page : 225-228

Effect on rat blood pressure: A test for allergenic potentialities of drugs

Correspondence Address:
S Prabhu

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Source of Support: None, Conflict of Interest: None

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Penicillin produced a prolonged tall in blood pressure of rats sensitized to it with Freund's adjuvant, fourteen days prior to the experiment. On the other hand. Streptomycin and Oxytetracycline, which are less notorious for causing anaphylactic shock, tailed to produce such an effect. The possibility of using such a test to predict the allergenic potentialities of drugs is discussed.


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