IPSIndian Journal of Pharmacology
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Year : 1977  |  Volume : 9  |  Issue : 2  |  Page : 159-162

Thermoregulation in guinea-pigs: The role of biogenic amines and PGE1

Correspondence Address:
K P Gupta

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Source of Support: None, Conflict of Interest: None

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Intracerebroventricular injection of adrenaline. nor-adrenaline, 5-hydroxytryptamine (5-HT). histamine and prostaglandin-E1 (POE1) through a chronically implanted cannula was observed on the rectal temperature of guinea pigs. Adrenaline, nor-adrenaline, 5-HT and histamine produced a fall whereas PGE2 produced a rise in temperature.


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