RESEARCH PAPER |
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Year : 1977 | Volume
: 9
| Issue : 2 | Page : 129-135 |
Pharmacological activity of some 1-adamantanamine derivatives
SK Kulkarni, RA Magarian, PN Kaul
Correspondence Address:
S K Kulkarni
 Source of Support: None, Conflict of Interest: None  | Check |

A series of Mannich condensation products containing the (-( 1-adamantylamino) propiophenone skeleton (Type I) and the O-(1 -ademantylaminomethyI) phenol (Type II) were tested for possible antiparkinson activity. Compound 3 had a significant anticatatonic effect and lacked anticholinergic activity. Both of these findings were comparable to amantadine hydrochloride.
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