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Year : 1976  |  Volume : 8  |  Issue : 3  |  Page : 167-175

Studies on Central Nervous System Depressants XVIII : Syntheses and Pharmacological Screening of Some Newer 5-Trimethoxybenzylidene Hydantoin Studies on Central Nervous System Depressants XVIII

Correspondence Address:
N K GurbaniI

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Source of Support: None, Conflict of Interest: None

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A number of N1 or N2-substituted-5(2,3,4-,2,4,5-, 2,4,6-and 3,4,5-trimethoxy benzvlidene) hydantoin or 2-thiohy-dantoins have been synthesised and evaluted for their CNS depressant and anticonvulsant activity. A new generic name 'Trimethotoin' is proposed for 2,4,6-trimethoxy benzene derivatives which exhibited potent CNS depressant and anticonvulsant actions.


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